%PDF-1.5 %?1 0 obj <> endobj 2 0 obj <>/Metadata 113 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /P <> BDC q 1 0 0 1 94.75 35.44999695 cm q 205.5 0 0 -50 0 50 cm /X1 Do Q Q EMC /P <> BDC q 1 0 0 1 371 28.19999695 cm q 117.34999847 0 0 -50.60000229 0 50.60000229 cm /X2 Do Q Q EMC /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 22.98600006 l -90 22.98600006 l h W n BT /FAAAAJ 9 Tf 1 0 0 -1 0 9.56900024 Tm 0 g [( )] TJ ET Q EMC q 1 0 0 1 90 72 cm /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 33.95500183 23.11899948 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.05999756 54.8769989 Tm /GS2 gs 0 g [(UB)1(E2S)] TJ ET EMC /P <> BDC BT /FAAABH 22 Tf 1 0 0 -1 151.53500366 54.8769989 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 328.23901367 54.8769989 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 78 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(UBE2S)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 93.34600067 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 177.34599304 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 111.53900146 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(UBE2S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.72100067 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.09500122 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.29699707 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.67100525 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.65100098 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.0249939 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.49899292 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 145.07800293 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(EPF5;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.50700378 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.8809967 12.82499981 Tm [(E2EPF;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 117.51499939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 119.88899994 12.82499981 Tm [(E2-E)-1(P)1(F)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.92799377 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 178.61700439 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 273.63400269 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 301.57299805 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15999985 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.5340004 12.55799961 Tm [(length)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.6609993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.03499985 12.55799961 Tm [(fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.3259964 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.69999695 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.08200073 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 330.51199341 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 358.45098877 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 386.39001465 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 414.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ubiquitin-)1(c)-1(onjugat)1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.08699799 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.58699799 11.72200012 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 131.96800232 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.46800232 11.72200012 Tm [(E2S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.88800049 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(EPF5;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.68000031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.18000031 11.72200012 Tm [(E2EPF;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 54.80799866 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.30799866 11.72200012 Tm [(E2-EP)1(F)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.66300201 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q16)-1(76)-1(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(NP_05)-1(53)-1(16)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.52399826 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 103.97499847 16.35000038 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 103.22499847 0.75 l 103.22499847 63.15000153 l 0.375 63.15000153 l h f* Q q -0.625 -0.25 m 104.22499847 -0.25 l 104.22499847 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 35.12200165 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 35.12200165 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 103.97499847 0.75 m 426.17501831 0.75 l 426.17501831 63.15000153 l 103.97499847 63.15000153 l h f* Q q 1 0 0 1 103.59999847 0 cm -0.625 -0.25 m 323.57501221 -0.25 l 323.57501221 64.15000153 l -0.625 64.15000153 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(This)] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.26199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 21.76199913 11.72200012 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.27799988 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.77799988 11.72200012 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.69499969 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.19499969 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.16999817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.66999817 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.93400574 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.43400574 11.72200012 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.27600098 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.77600098 11.72200012 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.7769928 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.2769928 11.72200012 Tm [(ubiquitin-)1(c)-1(onjugat)1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.36401367 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 268.86401367 11.72200012 Tm [(en)-1(z)1(y)-1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 302.24499512 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 306.74499512 11.72200012 Tm [(fa)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(mily)-1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.15299988 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.65299988 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.45999908 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.95999908 27.3220005 Tm [(en)-1(cod)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.46700287 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.96700287 27.3220005 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.27400208 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 122.77400208 27.3220005 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.33500671 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.83500671 27.3220005 Tm [(ab)1(l)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.05900574 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.55900574 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 165.63400269 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.13400269 27.3220005 Tm [(fo)1(rm)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.84500122 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 195.34500122 27.3220005 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.32000732 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 204.82000732 27.3220005 Tm [(th)1(iol)] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.22599792 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.72599792 27.3220005 Tm [(ester)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.89399719 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.39399719 27.3220005 Tm [(link)-1(ag)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.46798706 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.96798706 27.3220005 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.36401367 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ubiquitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.68099976 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.18099976 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 51.12200165 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.62200165 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.59700012 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.09700012 42.92200089 Tm [(ubiquitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.77799988 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.27799988 42.92200089 Tm [(activat)1(ing)] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.26300049 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 154.76300049 42.92200089 Tm [(en)-1(z)1(y)-1(me-d)1(e)-1(p)1(e)-1(ndent)] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.06300354 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.56300354 42.92200089 Tm [(manne)-1(r)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.77200317 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 283.27200317 42.92200089 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.24700928 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.74700928 42.92200089 Tm [(char)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(acteristic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.20600128 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.70600128 58.52199936 Tm [(pro)1(perty)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.01999664 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.51999664 58.52199936 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.36199951 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.86199951 58.52199936 Tm [(ubiquitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 136.54299927 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.04299927 58.52199936 Tm [(carrier)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.34199524 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.84199524 58.52199936 Tm [(pro)1(tein)-1(s)1(.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.48100281 58.52199936 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 0.75 m 103.59999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 17.10000038 m 103.59999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 33.45000076 m 103.59999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 49.80000305 m 103.59999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 66.15000153 m 103.59999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 82.5 m 103.59999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 98.84999847 m 103.59999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 103.59999847 115.19999695 m 103.59999847 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 177.6000061 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17501831 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 177.9750061 m 426.92501831 177.9750061 l S Q Q q 1 0 0 1 0 592.67901611 cm Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 0 obj <>stream ?? 丰满少妇被猛烈进入,丰满女老板BD高清,日韩国产成人无码AV在线,日本免费人成在线观看网站 º| | | Ϫ| | | | ǭ| | ̷| | | | ˮ| | | | | | | | | ʯ| | Զ| ʯʨ| | | ߺ| | | | ʼ| ̳| | | | | | | | http://444 http://444 http://444 http://444 http://444 http://444