%PDF-1.5 %?1 0 obj <> endobj 2 0 obj <>/Metadata 123 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /P <> BDC q 1 0 0 1 94.75 35.44999695 cm q 205.5 0 0 -50 0 50 cm /X1 Do Q Q EMC /P <> BDC q 1 0 0 1 371 28.19999695 cm q 117.34999847 0 0 -50.60000229 0 50.60000229 cm /X2 Do Q Q EMC /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 22.98600006 l -90 22.98600006 l h W n BT /FAAAAJ 9 Tf 1 0 0 -1 0 9.56900024 Tm 0 g [( )] TJ ET Q EMC q 1 0 0 1 90 72 cm /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 33.95500183 23.11899948 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97399902 54.8769989 Tm /GS2 gs 0 g [(UB)1(L3)] TJ ET EMC /P <> BDC BT /FAAABH 22 Tf 1 0 0 -1 145.6210022 54.8769989 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 322.32501221 54.8769989 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 78 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 68.25 12.82499981 Tm [(UBL3)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 93.05899811 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 177.05900574 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 111.53900146 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(UBL3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.18399811 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.55799866 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.76000214 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.13400269 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.11399841 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.48800659 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.96200562 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 145.07800293 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(HCG-1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 93.11100006 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.48500061 12.82499981 Tm [(PN)1(S)-1(C1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.43199921 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 178.61700439 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 273.63400269 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 301.57299805 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15999985 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.5340004 12.55799961 Tm [(length)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.6609993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.03499985 12.55799961 Tm [(fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.3259964 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.69999695 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.08200073 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 330.51199341 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 358.45098877 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 386.39001465 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -3.75 414.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ubiquitin-)1(l)-1(ike)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.37099838 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.87099838 11.72200012 Tm [(3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.14900208 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(HCG-1;)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.01199913 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.51200104 11.72200012 Tm [(PNSC1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.82800293 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(O95)-1(16)-1(4)] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.72399902 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC0)-1(59)-1(38)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 16.35000038 l 113.22499847 16.35000038 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 112.47499847 0.75 l 112.47499847 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 113.47499847 -0.25 l 113.47499847 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 113.22499847 0.75 m 426.17501831 0.75 l 426.17501831 156.75 l 113.22499847 156.75 l h f* Q q 1 0 0 1 112.84999847 0 cm -0.625 -0.25 m 314.32501221 -0.25 l 314.32501221 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Ub)1(iquitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.85400009 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.35400009 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.91500092 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 55.41500092 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.38999939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.88999939 11.72200012 Tm [(77)] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.44599915 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.94599915 11.72200012 Tm [(amino)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.01599884 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.51599884 11.72200012 Tm [(acid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.15600586 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.65600586 11.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.96299744 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.46299744 11.72200012 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.68499756 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 191.18499756 11.72200012 Tm [(ta)1(rgets)] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.33099365 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.83099365 11.72200012 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 261.3039856 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.8039856 11.72200012 Tm [(fo)1(r)] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.08200073 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 282.58200073 11.72200012 Tm [(degr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(ad)1(ation)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.72200012 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.22200012 27.3220005 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.73400116 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.23400116 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 66.23500061 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 70.73500061 27.3220005 Tm [(26)-1(S)] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.48500061 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.98500061 27.3220005 Tm [(pro)1(teasome.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.91900635 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.41900635 27.3220005 Tm [(Ub)1(iquitin-lik)-1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.96299744 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.46299744 27.3220005 Tm [(pro)1(tein)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.93600464 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.43600464 27.3220005 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.95401001 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.45401001 27.3220005 Tm [(not)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.07501221 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.57501221 27.3220005 Tm [(dir)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(ec)-1(t)1(l)-1(y)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.13100052 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 24.63100052 42.92200089 Tm [(involved)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.5 42.92200089 Tm [(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.44100189 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.94100189 42.92200089 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.2480011 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.7480011 42.92200089 Tm [(degra)1(dat)1(ion,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 168.69299316 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 173.19299316 42.92200089 Tm [(but)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.83999634 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.33999634 42.92200089 Tm [(ap)1(pear)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.32800293 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 226.82800293 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.90299988 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.40299988 42.92200089 Tm [(ha)1(ve)] TJ ET EMC /P <> BDC BT 1 0 0 -1 260.75 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 265.25 42.92200089 Tm [(many)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.9670105 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.4670105 42.92200089 Tm [(m)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(ec)-1(ha)1(n)-1(ist)1(ic)] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.50400162 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.00400162 58.52199936 Tm [(similarit)1(i)-1(es)] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.61499786 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.11499786 58.52199936 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.51100159 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.01100159 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.01199341 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.51199341 58.52199936 Tm [(ubiquitin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 177.19299316 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 181.69299316 58.52199936 Tm [(pa)1(thw)1(ay.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.32099915 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.82099915 58.52199936 Tm [(UBL3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.08399963 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 251.58399963 58.52199936 Tm [(\(ubiquitin-)1(l)-1(i)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(ke)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.00599957 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 14.50599957 74.12200165 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.81299973 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 50.31299973 74.12200165 Tm [(3\),)] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.76300049 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.26300049 74.12200165 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 82.51999664 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 87.01999664 74.12200165 Tm [(kn)-1(o)1(wn)] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.83899689 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 120.33899689 74.12200165 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.47999573 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.97999573 74.12200165 Tm [(membrane-anchored)] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.2539978 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 229.7539978 74.12200165 Tm [(ubiquitin-)1(fold)] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.32199097 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.82199097 74.12200165 Tm [(pr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(ot)1(e)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 22.12199974 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 26.62199974 89.72200012 Tm [(\(MUB\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.79299927 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.29299927 89.72200012 Tm [(or)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.4509964 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 71.9509964 89.72200012 Tm [(PNSC1,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.43299866 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.93299866 89.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.4940033 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.9940033 89.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.96900177 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.46899414 89.72200012 Tm [(11)-1(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 144.30200195 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.80200195 89.72200012 Tm [(amino)] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.87199402 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 180.37199402 89.72200012 Tm [(acid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 198.01199341 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.51199341 89.72200012 Tm [(membrane)] TJ ET EMC /P <> BDC BT 1 0 0 -1 249.29600525 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 253.79600525 89.72200012 Tm [(pro)1(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.10299683 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 289.60299683 89.72200012 Tm [(bel)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(onging)] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.72200012 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.22200012 105.3219986 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.29700089 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.79700089 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 62.79800034 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.29799652 105.3219986 Tm [(ubiquitin-)1(l)-1(ike)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.66899872 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.16900635 105.3219986 Tm [(fa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.41700745 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.91700745 105.3219986 Tm [(Hi)-1(g)1(hly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.72999573 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.22999573 105.3219986 Tm [(conse)-1(rv)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.30700684 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.80700684 105.3219986 Tm [(betw)1(e)-1(en)] TJ ET EMC /P <> BDC BT 1 0 0 -1 279.8789978 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 284.3789978 105.3219986 Tm [(spec)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(ies,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.83399963 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.33399963 120.92199707 Tm [(UBL3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.59700012 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.09700012 120.92199707 Tm [(contains)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.31199646 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.81199646 120.92199707 Tm [(tw)1(o)] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.99299622 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 106.49299622 120.92199707 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.08599854 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 149.58599854 120.92199707 Tm [(N-g)1(ly)-1(cosylat)1(i)-1(o)1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.26199341 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 221.76199341 120.92199707 Tm [(sites,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.11500549 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.61500549 120.92199707 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.58999634 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 257.08999634 120.92199707 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.68301392 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 300.18301392 120.92199707 Tm [(p)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(rot)1(e)-1(in)] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.55900002 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 30.05900002 136.52200317 Tm [(ki)-1(na)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.14699936 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.64699936 136.52200317 Tm [(C)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.66799927 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 72.16799927 136.52200317 Tm [(ph)1(osph)1(orylation)] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.94200134 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.44200134 136.52200317 Tm [(site,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.6289978 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 169.1289978 136.52200317 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.40600586 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.90600586 136.52200317 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.8809967 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.3809967 136.52200317 Tm [(po)1(ten)-1(t)1(ial)] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.97399902 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 242.47399902 136.52200317 Tm [(C-t)1(e)-1(r)1(min)-1(a)1(l)] TJ ET EMC /P <> BDC BT 1 0 0 -1 288.02801514 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 292.52801514 136.52200317 Tm [(pr)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(en)-1(ylat)1(ion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 39.80099869 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.30099869 152.12199402 Tm [(site.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 61.48799896 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 65.98799896 152.12199402 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.79499817 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.29499817 152.12199402 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.81099701 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 112.31099701 152.12199402 Tm [(en)-1(cod)1(i)-1(ng)] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.65299988 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.15299988 152.12199402 Tm [(UBL3)] TJ ET EMC /P <> BDC BT 1 0 0 -1 179.41600037 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 183.91600037 152.12199402 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.477005 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.977005 152.12199402 Tm [(localized)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.66000366 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.16000366 152.12199402 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.23500061 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.73500061 152.12199402 Tm [(chromos)1(om)] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 0.75 m 112.84999847 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 17.10000038 m 112.84999847 32.70000076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 33.45000076 m 112.84999847 49.05000305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 49.80000305 m 112.84999847 65.40000153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 66.15000153 m 112.84999847 81.75 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 82.5 m 112.84999847 98.09999847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 98.84999847 m 112.84999847 114.44999695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 112.84999847 115.19999695 m 112.84999847 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 426.55001831 0.75 m 426.55001831 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 0.375 m 426.92501831 0.375 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 16.72500038 m 426.17501831 16.72500038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 33.07500076 m 426.17501831 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17501831 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17501831 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17501831 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17501831 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17501831 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 271.57501221 m 426.92501831 271.57501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 0 obj <>stream ?? 丰满少妇被猛烈进入,丰满女老板BD高清,日韩国产成人无码AV在线,日本免费人成在线观看网站 Զ| ɽ| ɶ| ɽ| ƽ| ɽ| ɽ| ƽ| | | | ľ| | Դ| | | | Դ| | ӳ| Ϫ| ͤ| | | ¯| | | տ| ֦| | ̶| | ͨ| | | | Ϸ| | | | ߺ| http://444 http://444 http://444 http://444 http://444 http://444