%PDF-1.5 %?1 0 obj <> endobj 2 0 obj <>/Metadata 123 0 R>> endobj 3 0 obj <> endobj 4 0 obj <>/ExtGState<>/XObject<>>>/Group<>/StructParents 0/Tabs/S>> endobj 5 0 obj <>stream 1 0 0 -1 0 841.90002441 cm /P <> BDC q 1 0 0 1 94.75 35.44999695 cm q 205.5 0 0 -50 0 50 cm /X1 Do Q Q EMC /P <> BDC q 1 0 0 1 371 28.19999695 cm q 117.34999847 0 0 -50.60000229 0 50.60000229 cm /X2 Do Q Q EMC /Artifact <> BDC q 1 0 0 1 90 42.54999924 cm -90 0 m 505.29998779 0 l 505.29998779 22.98600006 l -90 22.98600006 l h W n BT /FAAAAJ 9 Tf 1 0 0 -1 0 9.56900024 Tm 0 g [( )] TJ ET Q EMC q 1 0 0 1 90 72 cm /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 33.95500183 23.11899948 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 83.60700226 54.8769989 Tm /GS2 gs 0 g [(THEM5)] TJ ET EMC /P <> BDC BT /FAAABH 22 Tf 1 0 0 -1 154.98899841 54.8769989 Tm 2 Tr 0.62857145 w 0 G [<0003>-4<0004>-4<0005>-4<0006>-4<0007>-4<0008>-4<0009>-4<000A>] TJ ET EMC /P <> BDC BT /FAAABC 22 Tf 1 0 0 -1 331.69299316 54.8769989 Tm 0 Tr /GS1 gs 0 g [( )] TJ ET EMC q 1 0 0 1 0 78 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<000B000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm [(THE)-1(M5)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 96.70999908 12.82499981 Tm [<0003000400050006000700080009000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 180.71000671 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 111.53900146 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0010000C000D000E000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(THE)-1(M5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 94.08499908 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 96.45899963 12.82499981 Tm [(Antigen)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.66099548 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.03500366 12.82499981 Tm [(\(Recombi)-1(nant)] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.01499939 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.38900757 12.82499981 Tm [(Pr)1(o)-1(te)1(i)-1(n\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 228.86300659 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 145.07800293 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0011>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<000D000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [(ACOT15)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.38600159 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 178.61700439 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0012>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 10.5 12.82499981 Tm [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 21 12.82499981 Tm [<0013000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<001400150005>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 94.5 12.82499981 Tm [(-20)] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 108.35800171 12.82499981 Tm [<0016000A>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 129.35800171 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 212.15600586 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<0017001800190011000F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 52.5 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 63 12.82499981 Tm /GS2 gs 0 g [<00030004>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 84 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 105 12.82499981 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 245.69500732 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001A001B>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 21 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 273.63400269 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 -5.4000001 301.57299805 cm q -0.75 -0.5 m 426.8500061 -0.5 l 426.8500061 29.43899918 l -0.75 29.43899918 l h W n q 1 0 0 1 5.4000001 0.5 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [(Fu)-1(ll)] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15999985 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 17.5340004 12.55799961 Tm [(length)] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.6609993 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.03499985 12.55799961 Tm [(fu)-1(sio)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 73.3259964 12.55799961 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 75.69999695 12.55799961 Tm [(protein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.08200073 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 0.5 w 0 0.5 m 0 28.43899918 l S Q q 0.5 w 426.1000061 0.5 m 426.1000061 28.43899918 l S Q q 0.5 w -0.25 0.25 m 426.3500061 0.25 l S Q q 0.5 w -0.25 28.68899918 m 426.3500061 28.68899918 l S Q Q q 1 0 0 1 0 330.51199341 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm [( )] TJ ET EMC Q q 1 0 0 1 0 358.45098877 cm /P <> BDC BT /FAAACB 10.5 Tf 1 0 0 -1 0 12.82499981 Tm /GS2 gs 0 g [<001C001D001E001F>] TJ ET EMC /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 42 12.82499981 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 0 386.39001465 cm /P <> BDC BT /FAAAAJ 10.5 Tf 1 0 0 -1 0 12.55799961 Tm /GS2 gs 0 g [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 5.25 12.55799961 Tm /GS1 gs 0 g [( )] TJ ET EMC Q q 1 0 0 1 -3.75 414.32901001 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Full)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.18099976 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.68099976 11.72200012 Tm [(name:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 48.35800171 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(th)1(ioe)-1(s)1(terase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.42699814 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.92699814 11.72200012 Tm [(superfa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 107.01100159 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 111.51100159 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 147.7749939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.2749939 11.72200012 Tm [(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.55299377 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q 1 0 0 1 0 16.35000038 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Synonyms:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 49.17900085 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(ACO)1(T)-1(15)] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.40200043 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 32.70000076 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Sw)1(iss)1(prot:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 46.64799881 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Q8N1)-1(Q8)] TJ ET EMC /P <> BDC BT 1 0 0 -1 37.81900024 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 49.04999924 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 23.19400024 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.69400024 11.72200012 Tm [(Acc)1(ess)1(io)-1(n:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 74.86499786 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(BC1)-1(12)-1(23)-1(9)] TJ ET EMC /P <> BDC BT 1 0 0 -1 43.33399963 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 65.40000153 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Purity:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 29.68899918 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(>85)-1(%)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 27.40399933 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.90399933 11.72200012 Tm [(as)] TJ ET EMC /P <> BDC BT 1 0 0 -1 41.04499817 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 45.54499817 11.72200012 Tm [(determine)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.54199982 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 100.04199982 11.72200012 Tm [(by)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.55400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 115.05400085 11.72200012 Tm [(Coo)1(massie)] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.75900269 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.25900269 11.72200012 Tm [(blue)] TJ ET EMC /P <> BDC BT 1 0 0 -1 185.05400085 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 189.55400085 11.72200012 Tm [(st)1(ain)-1(ed)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.852005 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.352005 11.72200012 Tm [(SDS-P)1(AGE)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.97000122 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 81.75 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Expres)1(sion)] TJ ET EMC /P <> BDC BT 1 0 0 -1 48.75299835 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.25299835 11.72200012 Tm [(system:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 87.68000031 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Escheric)-1(h)1(i)-1(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 47.53099823 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.03099823 11.72200012 Tm [(coli)] TJ ET EMC /P <> BDC BT 1 0 0 -1 67.05599976 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 98.09999847 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 16.35000038 l 0.375 16.35000038 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Tags)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 23.82299995 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 16.35000038 l 104.92500305 16.35000038 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 17.35000038 l -0.625 17.35000038 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(Hi)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.52200031 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 18.02199936 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 32.10599899 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.60599899 11.72200012 Tm [(C-Terminu)-1(s)1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 88.47499847 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 92.97499847 11.72200012 Tm [(GST)] TJ ET EMC /P <> BDC BT 1 0 0 -1 110.02100372 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 114.52100372 11.72200012 Tm [(ta)1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.60499573 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 133.10499573 11.72200012 Tm [(N-Terminu)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.10400391 11.72200012 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q Q q 1 0 0 1 0 114.44999695 cm q /GS2 gs 1 g 0.375 0.75 m 104.17500305 0.75 l 104.17500305 156.75 l 0.375 156.75 l h f* Q q -0.625 -0.25 m 105.17500305 -0.25 l 105.17500305 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACG 9 Tf 1 0 0 -1 0 81.92199707 Tm /GS2 gs 0.13333334 g [(Ba)1(ckgr)1(o)-1(und)1(:)] TJ ET EMC /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 57.29199982 81.92199707 Tm /GS1 gs 0 g [( )] TJ ET EMC Q Q q /GS2 gs 1 g 104.92500305 0.75 m 426.17498779 0.75 l 426.17498779 156.75 l 104.92500305 156.75 l h f* Q q 1 0 0 1 104.55000305 0 cm -0.625 -0.25 m 322.625 -0.25 l 322.625 157.75 l -0.625 157.75 l h W n q 1 0 0 1 3.75 0.75 cm /P <> BDC BT /FAAACJ 9 Tf 1 0 0 -1 0 11.72200012 Tm /GS2 gs 0.13333334 g [(TH)-1(E)1(M)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.13999939 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 35.63999939 11.72200012 Tm [(\(th)1(ioe)-1(s)1(terase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 91.07299805 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.57299805 11.72200012 Tm [(superfa)1(mi)-1(ly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 145.65699768 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 150.15699768 11.72200012 Tm [(member)] TJ ET EMC /P <> BDC BT 1 0 0 -1 186.42100525 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 190.92100525 11.72200012 Tm [(5\))] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.20500183 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.70500183 11.72200012 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 210.26600647 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 214.76600647 11.72200012 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 219.74099731 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 224.24099731 11.72200012 Tm [(24)-1(7)] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.07400513 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 244.57400513 11.72200012 Tm [(amino)] TJ ET EMC /P <> BDC BT 1 0 0 -1 271.64401245 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.14401245 11.72200012 Tm [(acid)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.78399658 11.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.28399658 11.72200012 Tm [(pro)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 27.3220005 Tm [(tein)] TJ ET EMC /P <> BDC BT 1 0 0 -1 16.39999962 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.89999962 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 38.12200165 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 42.62200165 27.3220005 Tm [(belongs)] TJ ET EMC /P <> BDC BT 1 0 0 -1 77.06199646 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.56199646 27.3220005 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.63700104 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 95.13700104 27.3220005 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 109.13800049 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.63800049 27.3220005 Tm [(th)1(ioe)-1(s)1(terase)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.06500244 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 170.56500244 27.3220005 Tm [(superfa)1(mi)-1(ly.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 222.81599426 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 227.31599426 27.3220005 Tm [(The)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.1230011 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.6230011 27.3220005 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.13900757 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.63900757 27.3220005 Tm [(th)1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.86099243 27.3220005 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 295.36099243 27.3220005 Tm [(en)-1(c)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 42.92200089 Tm [(od)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 20.75099945 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 25.25099945 42.92200089 Tm [(TH)-1(E)1(M)-1(5)] TJ ET EMC /P <> BDC BT 1 0 0 -1 56.39099884 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 60.89099884 42.92200089 Tm [(contains)] TJ ET EMC /P <> BDC BT 1 0 0 -1 97.10600281 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 101.60600281 42.92200089 Tm [(ne)-1(a)1(rly)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.82800293 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.32800293 42.92200089 Tm [(8,0)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 155.60600281 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 160.10600281 42.92200089 Tm [(ba)1(se)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.26699829 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.76699829 42.92200089 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.04400635 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 209.54400635 42.92200089 Tm [(map)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 232.86599731 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 237.36599731 42.92200089 Tm [(to)] TJ ET EMC /P <> BDC BT 1 0 0 -1 246.44099426 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 250.94099426 42.92200089 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.98199463 42.92200089 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 285.48199463 42.92200089 Tm [(chrom)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 58.52199936 Tm [(oso)1(me)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.14900017 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 33.64899826 58.52199936 Tm [(1q2)-1(1.3.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.84999847 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 69.34999847 58.52199936 Tm [(Chro)1(mosome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 127.65200043 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 132.1519928 58.52199936 Tm [(1)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.42999268 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.92999268 58.52199936 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 148.49099731 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 152.99099731 58.52199936 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 166.99200439 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.49200439 58.52199936 Tm [(larg)1(e)-1(st)] TJ ET EMC /P <> BDC BT 1 0 0 -1 200.67999268 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 205.17999268 58.52199936 Tm [(human)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.22099304 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 239.72099304 58.52199936 Tm [(chromos)1(ome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 296.51599121 58.52199936 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.01599121 58.52199936 Tm [(sp)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 74.12200165 Tm [(anning)] TJ ET EMC /P <> BDC BT 1 0 0 -1 29.76399994 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 34.26399994 74.12200165 Tm [(ab)1(out)] TJ ET EMC /P <> BDC BT 1 0 0 -1 59.60699844 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 64.10700226 74.12200165 Tm [(26)-1(0)] TJ ET EMC /P <> BDC BT 1 0 0 -1 79.94000244 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 84.44000244 74.12200165 Tm [(million)] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.72100067 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.22100067 74.12200165 Tm [(ba)1(se)] TJ ET EMC /P <> BDC BT 1 0 0 -1 138.21600342 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 142.71600342 74.12200165 Tm [(pa)1(i)-1(r)1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 163.43600464 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.93600464 74.12200165 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 184.21299744 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 188.71299744 74.12200165 Tm [(makin)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.71800232 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.21800232 74.12200165 Tm [(up)] TJ ET EMC /P <> BDC BT 1 0 0 -1 236.51199341 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 241.01199341 74.12200165 Tm [(8%)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.29699707 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.79699707 74.12200165 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 267.63900757 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 272.13900757 74.12200165 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 286.14001465 74.12200165 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 290.64001465 74.12200165 Tm [(hum)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 89.72200012 Tm [(an)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.52099991 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.02099991 89.72200012 Tm [(genome.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 52.85800171 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 57.35800171 89.72200012 Tm [(There)] TJ ET EMC /P <> BDC BT 1 0 0 -1 81.70800018 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 86.20800018 89.72200012 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 99.72599792 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 104.22599792 89.72200012 Tm [(ab)1(out)] TJ ET EMC /P <> BDC BT 1 0 0 -1 129.56900024 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 134.06900024 89.72200012 Tm [(3,0)-1(00)] TJ ET EMC /P <> BDC BT 1 0 0 -1 157.34700012 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 161.84700012 89.72200012 Tm [(gene)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.52900696 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 192.02900696 89.72200012 Tm [(on)] TJ ET EMC /P <> BDC BT 1 0 0 -1 203.29699707 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 207.79699707 89.72200012 Tm [(chromos)1(ome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 264.5920105 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 269.0920105 89.72200012 Tm [(1,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 276.53601074 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 281.03601074 89.72200012 Tm [(and)] TJ ET EMC /P <> BDC BT 1 0 0 -1 297.31298828 89.72200012 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 301.81298828 89.72200012 Tm [(co)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 105.3219986 Tm [(nsidering)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.10400009 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.60400009 105.3219986 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 58.60499954 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 63.10499954 105.3219986 Tm [(gr)1(e)-1(at)] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.73200226 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 90.23200226 105.3219986 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 124.04799652 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 128.54800415 105.3219986 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 137.38999939 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 141.88999939 105.3219986 Tm [(gene)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 167.57200623 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 172.07200623 105.3219986 Tm [(th)1(e)-1(r)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.61599731 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.11599731 105.3219986 Tm [(are)] TJ ET EMC /P <> BDC BT 1 0 0 -1 212.63400269 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 217.13400269 105.3219986 Tm [(also)] TJ ET EMC /P <> BDC BT 1 0 0 -1 234.39100647 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 238.89100647 105.3219986 Tm [(a)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.86599731 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.36599731 105.3219986 Tm [(larg)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 270.03500366 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 274.53500366 105.3219986 Tm [(number)] TJ ET EMC /P <> BDC BT 1 0 0 -1 308.35101318 105.3219986 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 120.92199707 Tm [(of)] TJ ET EMC /P <> BDC BT 1 0 0 -1 8.84200001 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 13.34200001 120.92199707 Tm [(diseases)] TJ ET EMC /P <> BDC BT 1 0 0 -1 49.17900085 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 53.67900085 120.92199707 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 98.80599976 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 103.30599976 120.92199707 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.70200348 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.20200348 120.92199707 Tm [(chromos)1(ome)] TJ ET EMC /P <> BDC BT 1 0 0 -1 182.99699402 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 187.49699402 120.92199707 Tm [(1.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 194.94099426 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 199.44099426 120.92199707 Tm [(Not)1(ably,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 235.88000488 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 240.38000488 120.92199707 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 254.3809967 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 258.88101196 120.92199707 Tm [(rar)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 275.83499146 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 280.33499146 120.92199707 Tm [(ag)1(in)-1(g)] TJ ET EMC /P <> BDC BT 1 0 0 -1 304.76400757 120.92199707 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 136.52200317 Tm [(disease)] TJ ET EMC /P <> BDC BT 1 0 0 -1 31.67099953 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 36.17100143 136.52200317 Tm [(Hu)-1(t)1(c)-1(h)1(i)-1(nso)1(n)-1(-)1(Gilfo)1(rd)] TJ ET EMC /P <> BDC BT 1 0 0 -1 118.87200165 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 123.37200165 136.52200317 Tm [(pro)1(geria)] TJ ET EMC /P <> BDC BT 1 0 0 -1 159.94799805 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 164.44799805 136.52200317 Tm [(is)] TJ ET EMC /P <> BDC BT 1 0 0 -1 171.00900269 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 175.50900269 136.52200317 Tm [(asso)1(c)-1(iat)1(e)-1(d)] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.63600159 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 225.13600159 136.52200317 Tm [(wit)1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 243.53199768 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 248.03199768 136.52200317 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 262.0329895 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 266.5329895 136.52200317 Tm [(LMNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 293.59500122 136.52200317 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 298.09500122 136.52200317 Tm [(ge)] TJ ET EMC /P <> BDC BT 1 0 0 -1 0 152.12199402 Tm [(ne)] TJ ET EMC /P <> BDC BT 1 0 0 -1 10.65200043 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 15.15200043 152.12199402 Tm [(wh)1(ic)-1(h)] TJ ET EMC /P <> BDC BT 1 0 0 -1 40.24900055 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 44.74900055 152.12199402 Tm [(en)-1(cod)1(e)-1(s)] TJ ET EMC /P <> BDC BT 1 0 0 -1 80.66600037 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 85.16600037 152.12199402 Tm [(lamin)] TJ ET EMC /P <> BDC BT 1 0 0 -1 108.91000366 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 113.41000366 152.12199402 Tm [(A.)] TJ ET EMC /P <> BDC BT 1 0 0 -1 121.90899658 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 126.40899658 152.12199402 Tm [(Wh)1(e)-1(n)] TJ ET EMC /P <> BDC BT 1 0 0 -1 151.76100159 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 156.26100159 152.12199402 Tm [(defec)-1(t)1(ive)-1(,)] TJ ET EMC /P <> BDC BT 1 0 0 -1 197.60899353 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 202.10899353 152.12199402 Tm [(th)1(e)] TJ ET EMC /P <> BDC BT 1 0 0 -1 216.11000061 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 220.61000061 152.12199402 Tm [(LMNA)] TJ ET EMC /P <> BDC BT 1 0 0 -1 247.67199707 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 252.17199707 152.12199402 Tm [(gene)] TJ ET EMC /P <> BDC BT 1 0 0 -1 273.68798828 152.12199402 Tm [( )] TJ ET EMC /P <> BDC BT 1 0 0 -1 278.18798828 152.12199402 Tm [(pro)1(duc)-1(t)] TJ ET EMC /P <> BDC BT 1 0 0 -1 312.26300049 152.12199402 Tm [( )] TJ ET EMC Q Q Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0 0.75 m 0 271.20001221 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 104.55000305 0.75 m 104.55000305 16.35000038 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 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0.75] 0 d 0.375 33.07500076 m 426.17498779 33.07500076 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 49.42500305 m 426.17498779 49.42500305 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 65.77500153 m 426.17498779 65.77500153 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 82.125 m 426.17498779 82.125 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 98.47499847 m 426.17498779 98.47499847 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d 0.375 114.82499695 m 426.17498779 114.82499695 l S Q q /GS1 gs 0.75686276 G 0.75 w [0.75 0.75] 0 d -0.375 271.57501221 m 426.92498779 271.57501221 l S Q Q Q 1 0 0 -1 0 841.90002441 cm endstream endobj 6 0 obj <>stream ?? 丰满少妇被猛烈进入,丰满女老板BD高清,日韩国产成人无码AV在线,日本免费人成在线观看网站 | ͼ| ƽ| | | ˲| | | ګ| | ʹ| ĵ| Ѿ| ²| ʯ| | ¡| | | | ŷ| Ļ| ¡| ƽ| | | °Ͷ| | | ʯ| | ˳| DZ| | | | | | ̨| | | http://444 http://444 http://444 http://444 http://444 http://444