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      • C12orf10 抗原(重组蛋白)

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      中文名称: C12orf10 抗原(重组蛋白)

      英文名称: C12orf10 Antigen (Recombinant Protein)

      别     名: chromosome 12 open reading frame 10; MYG; MYG1; Gamm1; MST024; MSTP024

      相关类别: 抗原

      储     存: 冷冻(-20℃)

      概     述

      Fusion protein corresponding to a region derived from 156-376 amino acids of human C12orf10

      技术规格

      Full name:

      chromosome 12 open reading frame 10

      Synonyms:

      MYG; MYG1; Gamm1; MST024; MSTP024

      Swissprot:

      Q9HB07

      Gene Accession:

      BC028904

      Purity:

      >85%, as determined by Coomassie blue stained SDS-PAGE

      Expression system:

      Escherichia coli

      Tags:

      His tag C-Terminus, GST tag N-Terminus

      Background:

      C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility.


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