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                • 兔抗TBC1D22A多克隆抗体

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                中文名称:兔抗TBC1D22A多克隆抗体

                英文名称: Anti-TBC1D22A rabbit polyclonal antibody

                别      名: C22orf4; HSC79E021

                相关类别: 一抗

                      存: 冷冻(-20℃)

                宿      主: Rabbit

                抗      原: TBC1D22A

                反应种属: Human, Mouse

                标  记 物: Unconjugate

                克隆类型: rabbit polyclonal

                技术规格

                Background:

                TBC1D22A (TBC1 domain family, member 22A), also known as C22orf4, is a 517 amino acid protein that contains one Rab-GAP TBC domain and is thought to function as a GTPase-activating protein for Rab family members. Multiple isoforms of TBC1D22A exist due to alternative splicing events. The gene encoding TBC1D22A maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, neurofibromatosis type 2, autism and schizophrenia. Additionally, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

                Applications:

                ELISA, IHC

                Name of antibody:

                TBC1D22A

                Immunogen:

                Fusion protein of human TBC1D22A

                Full name:

                TBC1 domain family, member 22A

                Synonyms:

                C22orf4; HSC79E021

                SwissProt:

                Q8WUA7

                ELISA Recommended dilution:

                2000-5000

                IHC positive control:

                Human thyroid cancer

                IHC Recommend dilution:

                25-100



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