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      • 兔抗TAF11多克隆抗体

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      中文名称:兔抗TAF11多克隆抗体

      英文名称: Anti-TAF11 rabbit polyclonal antibody

            名: TAF2I; PRO2134; TAFII28; MGC:15243

      相关类别: 一抗

            存: 冷冻(-20℃)

      宿      主: Rabbit

            原: TAF11

      反应种属: Human, Mouse, Rat

      标  记 物: Unconjugate

      克隆类型: rabbit polyclonal

      技术规格

      Background:

      Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.

      Applications:

      ELISA, WB, IHC

      Name of antibody:

      TAF11

      Immunogen:

      Fusion protein of human TAF11

      Full name:

      TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa

      Synonyms:

      TAF2I; PRO2134; TAFII28; MGC:15243

      SwissProt:

      Q15544

      ELISA Recommended dilution:

      2000-5000

      IHC positive control:

      Human thyroid cancer

      IHC Recommend dilution:

      35-150

      WB Predicted band size:

      23 kDa

      WB Positive control:

      Mouse brain and heart tissue, Jurkat, K562 and hela cells

      WB Recommended dilution:

      500-2000





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