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      • UBB抗原(重组蛋白)

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        • 品牌 : 通蔚生物
        • 目录号 : TW20217
        • 应用 : 仅供科研使用
        • 保存条件 : 低温保存
        • 货期 : 现货
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      中文名称: UBB抗原(重组蛋白)

      英文名称: UBB Antigen (Recombinant Protein)

      储     存:  冷冻(-20℃)

      相关类别: 抗原

      概     述

      Fusion protein corresponding to a region derived from 101-229 amino acids of human UBB

      技术规格

      Full name:

      ubiquitin B

      Swissprot:

      P0CG47

      Gene Accession:

      BC009301

      Purity:

      >85%, as determined by Coomassie blue stained SDS-PAGE

      Expression system:

      Escherichia coli

      Tags:

      His tag C-Terminus, GST tag N-Terminus

      Background:

      This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants.



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