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      • TIA1抗原(重组蛋白)

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        • 目录号 : TW20023
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      中文名称: TIA1抗原(重组蛋白)

      英文名称: TIA1 Antigen (Recombinant Protein)

      别     名:  WDM; TIA-1

      储     存:  冷冻(-20℃) 

      相关类别: 抗原

      概     述

      Full length fusion protein

      技术规格

      Full name:

      TIA1 cytotoxic granule-associated RNA binding protein

      Synonyms:

      WDM; TIA-1

      Swissprot:

      P31483

      Gene Accession:

      BC015944

      Purity:

      >85%, as determined by Coomassie blue stained SDS-PAGE

      Expression system:

      Escherichia coli

      Tags:

      His tag C-Terminus, GST tag N-Terminus

      Background:

      The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15-kDa protein that is thought to be derived from the carboxyl terminus of the 40-kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.



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